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Cholesterol Overload in Macrophages Drives Metabolic Dysfunction-Associated Steatohepatitis Via Inhibiting 7-Dehydrocholesterol Reductase in Mice

Xiaoxiao Li,Kai Wang, Yunhong Sun, Yirong Wang, Jiaxuan Wu,Yanqi Dang,Meng Li,Wenjun Zhou

Journal of Translational Medicine(2024)

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Key words
Metabolic dysfunction-associated steatohepatitis,Hepatic macrophages,Cholesterol overload,7-dehydrocholesterol reductase,Inflammation
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