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Comprehensive Multi-Omics Analysis Elucidates Colchicine-Induced Toxicity Mechanisms and Unveils the Therapeutic Potential of MLN4924 and Kinase Inhibitors

Lin-hui Zhai,Xing-long Jia,Yu-lu Chen,Mu-yin Liu, Jing-dan Zhang,Shao-jie Ma,Xiu-jun Wang,Wen-hao Cheng,Jing-liang He,Jiao-jiao Zhou,Ling-yi Zuo,Mei-qi Zhang,Qing Yuan,Meng-han Xu,Jing Ji,Min-jia Tan,Bin Liu

ACTA PHARMACOLOGICA SINICA（2024）

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Key words
colchicine,MLN4924,multi-omics analysis,phosphoproteomics,ubiquitinomics,kinase inhibitor
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