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Multiomic Sequencing Reveals Distinctive Gene Expression and Epigenetic Alterations Associated with Primary Sclerosing Cholangitis Development in Treatment-Naïve Pediatric Ulcerative Colitis

Alejandra Rodriguez-Sosa, Ololade Lawal,Ciaran Mcdonnell,Luke Grant, John O'Brien, Muhammad Ali, Ian Stephens,Grainne Kirwan,Flavia Genua,Alexander Kel,Anna Dominik,Roisin Stack,Gregory Yochum, Michael Mcdermot,Glen Doherty,Seamus Hussey,Sudipto Das

GASTRO HEP ADVANCES（2025）

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Key words
Primary Sclerosing Cholangitis,Ulcerative Colitis,Transcriptional Regulation,Methylation Profiling
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