Low PD-L1 Expression, MAP2K2 Alterations, and Enriched HPV Gene Signatures Characterize Brain Metastases in Head and Neck Squamous Cell Carcinoma

Michael J. Dennis,Dean C. Pavlick,Alec Kacew,Michael Wotman,Laura E. MacConaill,Stephanie M. Jones,Kathleen L. Pfaff,Scott J. Rodig,Stephen Eacker,Maika Malig, Emily Reister,David Piccioni,Santosh Kesari,Kartik Sehgal,Robert I. Haddad,Ezra Cohen,Marshall R. Posner,Ida Deichaite,Glenn J. Hanna

Journal of Translational Medicine（2024）

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关键词

Brain metastasis,Head and neck squamous cell carcinoma,Head and neck cancer,Next-generation sequencing,Human papillomavirus,PD-L1,TSC1,MAP2K2,HPV,Molecular

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