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Dominant Negative Effects of Gln50arg Mutation in the Egf-1 Domain of Factor IX Causes Severe Haemophilia B That Negatively Affects Factor IX Replacement Therapy

Tirsa van Duijl, Kyra Smit, Nadia Freato,Joost Meijers, Alette Kooiker, Henrike Hamer,Maartje van den Biggelaar

HAEMOPHILIA（2024）

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Key words
haemophilia B,proteomics,thrombin generation
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