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Combinational Regenerative Inductive Effect of Bio-Adhesive Hybrid Hydrogels Conjugated with Hipsc-Derived Myofibers and Its Derived EVs for Volumetric Muscle Regeneration

Jiseong Kim,Myung Chul Lee,Jieun Jeon,Alejandra Rodriguez-dela Rosa,Yori Endo, Da-Seul Kim, Andrea Donaxi Madrigal-Salazar,Jeong Wook Seo,Hyeseon Lee,Ki-Tae Kim,Jae- Moon,Seung Gwa Park, Mariana Carolina Lopez-Pacheco,Abdulhameed F. Alkhateeb,Nebras Sobahi,Nicole Bassous, Wenpeng Liu, Jae Seo Lee, Seongsoo Kim,Dilara Yilmaz Aykut, Mahmoud Lotfi Nasr,Mohammad Asif Hussain,Soo-Hong Lee,Woo-Jin Kim,Olivier Pourquie,Indranil Sinha,Su Ryon Shin

BIOACTIVE MATERIALS（2025）

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Key words
Human induced pluripotent stem cells,Extracellular vesicles,Bio-adhesive hydrogel,Muscle regeneration,Volumetric muscle loss
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