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Preclinical Assessment of the PI3Kα Selective Inhibitor Inavolisib and Prediction of Its Pharmacokinetics and Efficacious Dose in Human.

Laurent Salphati,Jodie Pang,Emile G. Plise,Jonathan Cheong,Marie-Gabrielle Braun,Lori S. Friedman, Rebecca Hong Thibodeau,Allan Jaochico, Ryan Johnson,Ning Liu,Michelle Nannini,Deepak Sampath,Kyung Song, Emily J. Hannan,Steven T. Staben

XENOBIOTICA（2024）

Cited 2|Views3
Key words
PI3K,PI3K inhibitor,PI3K mutant,PK/PD modelling,PBPK modelling,pharmacokinetics,efficacious dose
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