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The Singular French PCSK9-p.Ser127Arg Gain-of-function Variant: a Significant Player in Cholesterol Levels from a 775-Year-old Common Ancestor

Yara Azar,Thomas E. Ludwig, Hugo Le Bon,Thea Bismo Strom,Olivier Bluteau,Mathilde Di-Filippo,Alain Carrie, Hedi Chtioui,Sophie Beliard,Oriane Marmontel, Annie Fonteille, Maite Gebhart,Noel Peretti,Philippe Moulin,Jean Ferrieres,Alain Pradignac,Michel Farnier,Antonio Gallo,Cecile Yelnik,Dirk Blom,Emmanuelle Genin,Martin Proven Bogsrud,Trond P. Leren,Catherine Boileau,Marianne Abifadel,Jean-Pierre Rabes,Mathilde Varret

ATHEROSCLEROSIS（2024）

Cited 0|Views8
Key words
Hypercholesterolemia,ADH,PCSK9,Founder variant,LDLR,LDL-C,HDL-C
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