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Design, Synthesis, and Biological Evaluation of Diphenyl Ether Substituted Quinazolin-4-amine Derivatives As Potent EGFRL858R/T790M/C797S Inhibitors

Dou, Xingsen Zhang, Jie Wang,Gulinuer Wumaier,Yunjin Qiao,Lijuan Xie, Wenzhe Jiang,Wenjie Sha,Wenjie Li,Wenyi Mei,Chen Zhang,Huan He,Caolin Wang, Lingkang Wu,Yanyan Diao,Lili Zhu,Zhenjiang Zhao,Zhuo Chen,Yufang Xu,Shengqing Li,Honglin Li

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（2024）

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关键词
NSCLC,EGFR,C797S mutation,Resistance,4-Anilinoquinazoline
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