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KMT2D Deficiency Leads to Cellular Developmental Disorders and Enhancer Dysregulation in Neural-Crest-containing Brain Organoids

Ziyun Shan,Yingying Zhao, Xiuyu Chen, Guodong Zhan,Junju Huang,Xuejie Yang, Chongshen Xu,Ning Guo, Zhi Xiong,Fang Wu,Yujian Liu,He Liu,Biyuan Chen, Bingqiu Chen, Jiaoyang Sun,Jiangping He, Yiping Guo,Shangtao Cao,Kaixin Wu, Rui Mao,Guangming Wu,Lihui Lin,Xiaobing Zou,Jie Wang,Jiekai Chen

SCIENCE BULLETIN（2024）

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Key words
KMT2D,Enhancer,Niche,Cerebral organoids,Single-cell multiome
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