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Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity That Targets PfATP4

Trent D. Ashton,Petar P. S. Calic,Madeline G. Dans, Zi Kang Ooi, Qingmiao Zhou,Katie Loi,Kate E. Jarman,Josephine Palandri,Deyun Qiu,Adele M. Lehane, Bikash Maity,Nirupam De,Mufuliat T. Famodimu,Michael J. Delves, Emma Y. Mao,Maria R. Gancheva,Danny W. Wilson,Mrittika Chowdury,Tania F. de Koning-Ward,Delphine Baud,Stephen Brand,Paul F. Jackson,Alan F. Cowman,Brad E. Sleebs

ChemMedChem（2024）

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Key words
Antimalarial,Malaria,PfATP4,<italic>Plasmodium</italic>,Quinazolinone
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