Synthetic Lethality of Combined ULK1 Defection and P53 Restoration Induce Pyroptosis by Directly Upregulating GSDME Transcription and Cleavage Activation Through ROS/NLRP3 Signaling
Journal of Experimental & Clinical Cancer Research(2024)
Key words
MDM2 inhibitor,Mitophagy,Pyroptosis,Reactive oxygen species,TP53,ULK1
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