Mispitools: An R Package for Comprehensive Statistical Methods in Kinship Inference

Abstract The search for a missing persons is a complex process that involves comparison of data from two entities: unidentified persons (UP), who may be alive or deceased, and missing persons (MP), whose whereabouts are unknown. Although existing tools support DNA-based kinship analyzes for the search, they typically do not integrate or statistically evaluate diverse lines of evidence collected throughout the investigative process. Examples of alternative lines of evidence are pigmentation traits, biological sex, and age, among others. The package Mispitools fills this gap by providing comprehensive statistical methods adapted to a holistic investigation workflow. Mispitools systematically assesses the data from each investigative stage, computing the statistical weight of various types of evidence through a likelihood ratio (LR) approach. It also provides models for combining obtained LRs. Furthermore, Mispitools offers customized visualizations and a user-friendly interface, broadening its applicability among forensic practitioners and genealogical researchers. ### Competing Interest Statement The authors have declared no competing interest.