SILAC-based Quantification Reveals Modulation of the Immunopeptidome in BRAF and MEK Inhibitor Sensitive and Resistant Melanoma Cells

Melissa Bernhardt,Anne Rech, Marion Berthold, Melina Lappe, Jan-Niklas Herbel,Florian Erhard,Annette Paschen,Bastian Schilling,Andreas Schlosser

FRONTIERS IN IMMUNOLOGY（2025）

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mass spectrometry,stable isotope labeling,HLA-I peptides,T-cell epitopes,de novo peptide sequencing,cryptic HLA peptides,melanoma,MAPK pathway inhibition

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