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Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated with Ocular Hypertension.

Chia-Chen Hsu, Fang-Pai Lin, Hao-Chen Tseng, Pin Kuan Ho,Yi-Hsun Chen,Yann-Guang Chen,Da-Wen Lu,Yi-Hao Chen, Jian-Liang Chou,Hsin-Chih Chen,Yu Chuan Huang

Investigative Ophthalmology & Visual Science(2024)

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关键词
primary open-angle glaucoma (POAG),intraocular pressure (IOP),microbead- induced,ocular hypertension (OHT),Rho-kinase inhibitor (ROCK),trabecular meshwork (TM),aqueous humor (AH) outflow,myosin light chain,myosin light chain phosphatase (MLCP),myosin light chain kinase (MYLK),early/late-onset POAG,whole transcriptome sequencing,ITRI-E-(S)-4046
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