T-cell Specific in Vivo Gene Delivery with DART-AAVs Targeted to CD8.

Muhammed Burak Demircan, Luca J. Zinser,Alexander Michels, Mar Guaza-Lasheras, Fabian John, Johanna M. Gorol,Samuel A. Theuerkauf, Dorothee M. Guenther,Dirk Grimm, Florian R. Greten,Petr Chlanda,Frederic B. Thalheimer,Christian J. Buchholz

Molecular Therapy（2024）

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Key words

Gene therapy,viral vectors,Targeted AAV,AAV capsid engineering,Targeted gene therapy,In vivo gene therapy,In vivo delivery,T cell targeting,Receptor-targeting,DART-AAVs,CD8 targeting,CD8-AAV,T cell activation

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