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Identification of Reversible OATP1B1 and Time-Dependent CYP3A4 Inhibition As the Major Risk Factors for Drug-Induced Cholestasis (DIC)

Vlasia Kastrinou-Lampou,Raquel Rodríguez-Pérez,Birk Poller,Felix Huth,Zsuzsanna Gáborik,Beáta Mártonné-Tóth,Csilla Temesszentandrási-Ambrus,Heiko S. Schadt,Gerd A. Kullak-Ublick,Michael Arand,Gian Camenisch

Archives of Toxicology（2024）

引用 1|浏览13
关键词
Drug-induced cholestasis,Cholestatic DILI,CYP3A4,OATP1B1,Bile acids
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