Safety Guided Process Development and Scale-Up of the Highly Energetic Compound 4-Methyl-1,2,5-oxadiazole-3-carboxylic Acid

Qiang Yang, Yu Lu,Han Xia, Vishaal Gopalakrishnan,Scott A. Frank, Yungang He, Lixuan Liang,Xin Zhang, Ping Huang,Chuanren Liu, Jing Chen, Qicheng Ma, Sha Li, Li Fan

ORGANIC PROCESS RESEARCH & DEVELOPMENT（2024）

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Key words

4-methyl-1,2,5-oxadiazole-3-carboxylicacid,thermalinstability hazards,highly energetic compounds,process safety evaluation,continuous flow process

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