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The Reovirus Variant RP116 is Oncolytic in Immunocompetent Models and Generates Reduced Neutralizing Antibodies to Type 3 Dearing

Ki-Hoon Song,Xiao Xiang, So Hyun Lee, Jong Kyu Woo,Gansukh Enkhtaivan, Carlos Rios Giraldo, You-Rim Lee, Yeo Jin Jeong, Salar Pashangzadeh, Negar Shari,An-Dao Yang,Huy-Dung Hoang,Nam-Hyuk Cho,Yeon-Sook Lee,Dong Guk Park,Tommy Alain

MOLECULAR THERAPY ONCOLOGY（2024）

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Key words
MT: Regular Issue,reovirus variant,truncated Sigma1,determinant for reovirus oncolysis,ICI combination,reduction of neutralization,sequential tandem therapy
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