Integrative Dynamic MultiOMICs Analysis Identifies Cell Cycle and DNA Damage Response Phenotypes As Downstream Consequences of Using the PRMT5 Inhibitor AZD3470 Ted Hong , Steven Criscione , Andrew Jarnuczak , Jelena Urosevic , Stephanie Ashenden , Ghaith Hamza , Praveen Kumar , Nevena Cvetesic , Lauren Bradshaw , Shaun Moore , Daniel Karl , Tianhui Zhang , Abel Sousa , Jonathan Cairns , Anthony Iannetta , Andrew Zhang , Eric Miele , John Reicha , Chris Chambers , Ramy Elgendy , Julia Lindgren , Daniel Jachimowicz , Maryam Clausen , Graham Belfield , Tony Cheung , Michael Grondine , James T. Lynch , Ho Man Chan , Susan Critchlow , Emma Dean CANCER RESEARCH(2024)
关键词
AZD3470, NSCLC, PRMT5 Inhibition, Chromatin Accessibility, Alternative Splicing, DNA Repair, ATM Gene
AI 理解论文
溯源树
样例