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First Multikilogram Synthesis of the Next-Generation Oral Selective ERα Degrader Camizestrant

Matthew R. Tatton,Gordon S. Currie, Bradley Adams,Carl-Johan Aurell, Karl Broberg,Andrew D. Campbell,Kuangchu Dai,Marcus Malmgren, Andrew Ikin,Sophie L. M. Janbon, Martin Sims, Joanna Hemming-Taylor, Victoria Winterbottom

Organic Process Research & Development(2024)

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关键词
Pictet-Spengler reaction,Buchwald-Hartwigcoupling,selective ER alpha degrader,SERD,indazole
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