Evaluation of the Factors Influencing Mortality in Patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Multicenter Study of 166 Patients

Funda Erduran, Esra Adışen, Selma Emre, Yıldız Hayran, Emel Bülbül Başkan, Serkan Yazıcı, Aslı Bilgiç, Erkan Alpsoy, Sibel Doğan Günaydın, Leyla Elmas, Melih Akyol, RukiyeYasak Güner, Deniz Aksu Arıca, Yağmur Aypek, Tülin Ergun, Dilan Karavelioğlu, Ayça Cordan Yazıcı, Kübra Aydoğan, Dilek Bayramgürler, Rebiay Kıran, Hilal Kaya Erdoğan, Ersoy Acer, Akın Aktaş

Dermatology and Therapy（2024）

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摘要

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening acute mucocutaneous disorders usually triggered by drugs. In this study, we aimed to evaluate the factors affecting mortality in patients with SJS-TEN. Our study is a retrospective cohort study, analyzing data collected from a total of 12 tertiary care centers between April 2012 and April 2022. The study included 59 males and 107 females, a total of 166 patients, with an average age of 50.91 ± 21.25 years. Disease classification was TEN in 50

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关键词

Stevens-Johnson syndrome,Toxic epidermal necrolysis,SCORTEN,Plasmapheresis,Mortality,Survival

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