Peptide Macrocyclisation via Intramolecular Interception of Visible-Light-Mediated Desulfurisation

Frances R. Smith, Declan Meehan,Rhys C. Griffiths, Harriet J. Knowles, Peiyu Zhang,Huw Williams,Andrew Wilson,Nicholas J. Mitchell

Chemical Science（2024）

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摘要

Synthetic methods that enable the macrocyclisation of peptides facilitate the development of more effective therapeutic and diagnostic tools. Herein we report a peptide cyclisation strategy based on intramolecular interception of...

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