Uncommon reaction in 4-formyl phenols - substitution of the formyl group

PROCEEDINGS OF THE ESTONIAN ACADEMY OF SCIENCES(2024)

引用 0|浏览0
暂无评分
摘要
4-formyl phenols with electron donating groups in ortho-position react with active alkyl halides in three directions: Williamson reaction up to 48%, aromatic substitution of the formyl group up to 36%, and addition to the ortho-position with dearomatization of the ring up to 10%. The ratio of the products depends on the substituents in the benzene ring and the used alkali and additives.
更多
查看译文
关键词
alkylation,phenolates,electrophilic substitution of formyl group,electrophilic addition to arenes,dearomatization.
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要