Ethnobotanical Use, Phytochemistry and Pharmacological Activities of Clerodendrum colebrookianium (Lamiaceae)

Clerodendrum colebrookianium (CC) is a small shrub belonging to the genus Clerondendrum and the family Lamiaceae that is widely distributed in southeast Asian countries like India and China. The plant generally grows in the wet and arid regions of the globe. It has four angled branches that bear flowers along with heart-shaped leaves. This review aims to provide vast knowledge about the pharmacological activities, ethnobotany uses, and the phytochemicals present in the plant. Additionally, it will advance our understanding of the plant's therapeutic potential in the years to come. Much available literature regarding the pharmacological properties, ethnobotany uses, and phytochemistry of C .colebrookianium was collected from a series of scientific resources including PubMed and Google Scholar. Many Asian countries have a long history of using plants from the Clerodendrum genus for various medicinal purposes. Different extracts of CC have demonstrated a wide range of pharmacological effects, including those that are antihypertensive, hepatoprotective, analgesic, antidiabetic and many more. Phytoconstituents like Steroids- daucosterol, beta-sitosterol, colebrin-A, colebrin-B, colebrin-C, colebrin-D, colebrin-D and Glycoside- clerosterol 3 beta-O-[beta-D-glucoside], Clerosterol (24S/3) (poriferasta-5,25(26)-dien-3-ol, sitosterol and octacosanol were reported to be present in this plant. This article offers a summary of the most recent research on the pharmacological, traditional uses and some of the phytochemicals of C. colebrookianium walp. Even though it offers a wide range of medical benefits, many of its traditional uses for health have not been well researched. The entire therapeutic potential of these plants for treating a variety of other disorders could be discovered with the aid of in-depth research and studies on the phytoconstituents of the plant and their active principles.