Supplementary Figure S1 from The Antipsychotic Drug Penfluridol Inhibits N-Linked Glycoprotein Processing and Enhances T-cell–Mediated Tumor Immunity

Wenlong Xu, Yuqi Wang,Na Zhang, Xiaofeng Lin, Di Zhu, Cheng Shen, Xiaobo Wang, Haiyang Li, Jinjiang Xue,Qian Yu,Xinyi Lu, Lu Zhou,Qingli He, Zhijun Tang, Shaodan He,Jianjun Fan,Jianbo Pan,Jiangjiang Tang,Wei Jiang,Mingliang Ye, Fanghui Lu,Zengxia Li,Yongjun Dang

crossref(2024)

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摘要

(a) Western blot analysis of glycoprotein patterns in MDA-MB-231 cells after treatment with the indicated concentrations of penfluridol for 24 hours. Red arrowhead, immature glycoproteins. (b) Western blot analysis of protein expression pattern of ACE2 in HEK293T cells after treatment with the indicated concentrations of penfluridol for 24 hours. (c) In HEK293T cells, FLAG-tagged ACE2 was treated for 24 hours, collected by immunoprecipitation, subjected to SDS-PAGE, and analyzed by western blot. (d) Pearson correlation coefficient of three independent groups of (c) through N-glycan profiling.

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