Аналіз якості життя в пацієнтів з ішемічною хворобою серця та супутньою патологією аортального клапана у віддалений період після протезування аортального клапана з реваскуляризацією міокарда Analysis of the quality of life in patients with coronary heart disease and concomitant aortic valve pathology in the long-term period after aortic valve replacement with myocardial revascularization

The aim – to conduct an analysis of the quality of life in the long-term period after the use of a hybrid approach, involving a combination of surgical aortic valve replacement (AVR) and endovascular methods of myocardial revascularization, in patients with coronary heart disease and an aortic valve disease.Materials and methods. For this one-center study, medical records of adult patients (over 18 years old) who underwent surgical AVR along with myocardial revascularization in the period from 2018 to 2022 were selected.Results and discussion. We selected 130 patients who underwent AVR together with myocardial revascularization (the first group (n = 51) – a combination of AVR and percutaneous coronary interventions (PCI); the second group (n = 79) – a combination of AVR and coronary artery bypass grafting (CABG). Damage to the left main coronary artery was recorded by 5.60 times less often (p = 0.018) in the patients of the first group compared to the patients of the second group. The duration of cardiopulmonary bypass and aorta cross clamping in the patients of the first group was, respectively, by 1.5 times and by 1.4 times significantly lower compared to the second group (p = 0.0001). The pain index after 6 months according to the SF-36 questionnaire was found to be 13.5 % (p = 0.017) significantly higher in patients of the first group compared to the second group, while other indicators did not differ among the study groups.Conclusions. Patients with the hybrid approach of treatment were characterized by a similar level of postoperative complications with the surgical group. At the same time, this cohort of patients had a better SF-36 pain index 6 months after the hybrid intervention.