Antimicrobial Nano-Coatings of Ti Surfaces for Anti-Inflammatory Aims in Dental Implants

Introduction: Coating of dental implants with nanoparticles can lead to improved fixation of implants. Aim: The aim of this study was to review the reported antimicrobial nano-coatings of Ti surfaces (dental implants) for anti-inflammatory, tissue integration, and osteogeneration aims. Methods: The data were collected from Google Scholar, PubMed, and Scopus sources. Results: The results showed that the antimicrobial nano-coatings of Ti surfaces exhibited a reduction in initial bacterial adhesion, concomitantly with an increase in the attachment of human gingival fibroblasts. In addition, the application of these surfaces resulted in anti-inflammatory effects with different mechanisms. Some nano-coated titanium surfaces have also shown enhanced hydrophilicity and corrosion resistance, aiding the adhesion and proliferation of osteoblasts. Conclusion: Coating Ti surfaces with antimicrobial nanoparticles can improve soft tissue integration and osteogeneration, leading to improved fixation of implants. Moreover, such coatings may profit biocompatible surfaces with a controlled release profile for the antimicrobial agents.