Comparative Analysis of Sulfated and Sulfonated Disaccharide Analogs as TLR4 Modulators and Heparanase Inhibitors

Jamal El Abid,Dindet Steve-Evanes Koffi Teki,Abed Bil,Agnès Denys, Aurélie Vallin, corentin Lefebvre,Fabrice Allain,Vincent Chagnault,Jose Kovensky

New Journal of Chemistry（2024）

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摘要

This article delves into the synthesis and biological evaluation of sulfated and sulfonated disaccharide analogs, exploring their interactions with Toll-Like Receptor 4 (TLR4) and their potential as drug candidates for...

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