Molecule engineering strategy of toll-like receptor 7/8 agonists designed for potentiate immune stimuli activation

Liuwei Gu, Xiaojie Kong, Mengyan Li,Rui Chen, Ke Xu,Guo Li,Yuling Qin,Li Wu

Chemical Communications(2024)

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摘要
Toll-like receptor 7/8 (TLR 7/8) agonists serve as a promising class of pattern recognition receptors that effectively evoke the innate immune response, making them promising immunomodulatory agents for tumor immunotherapy....
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