Comparative Antimicrobial Activity of Amikacin and Gentamicin on Clinically Important Bacteria

Bhoj R Singh, Himani Agri,Ravichandran Karthikeyan, Varsha Jayakumar

Journal of Pharmacology & Clinical Toxicology（2023）

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摘要

Aminoglycosides discovered 80 years ago are still the drug of choice for combating a range of infections, including those caused by multiple drug-resistant (MDR) strains of bacteria. These bactericidal antibiotics are nephrotoxic and ototoxic and often not permitted for therapeutic use in animals and birds.

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