Ethanol-assisted mechanochemical asymmetric cross-dehydrogenative coupling reaction with recoverable chiral amine/NaCl for accessing chiral α-alkyl α-glycine derivatives

Jingbo Yu, Hong Chen, Ziwen Zhang, Yuxin Fang,Tao Ying,Weike Su

Green Chemistry(2024)

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摘要
Chiral α-alkyl α-glycine acids are a prevalent structural motif found in pharmaceuticals and natural products, making them a significant dimension for exploration in modern pharmaceutical and medicinal chemistry. However, the...
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