Joint EURADOS-EANM initiative for an advanced computational framework for the assessment of external dose rates from nuclear medicine patients

Lara Struelens, Christelle Huet, David Broggio,Jérémie Dabin,Laurent Desorgher,Augusto Giussani,Wei Bo Li, Dietmar Nosske, Yi-Kang Lee, Lidia Cunha, Maria J. R. Carapinha, Mario Medvedec,Peter Covens

EJNMMI Physics(2024)

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摘要
In order to ensure adequate radiation protection of critical groups such as staff, caregivers and the general public coming into proximity of nuclear medicine (NM) patients, it is necessary to consider the impact of the radiation emitted by the patients during their stay at the hospital or after leaving the hospital. Current risk assessments are based on ambient dose rate measurements in a single position at a specified distance from the patient and carried out at several time points after administration of the radiopharmaceutical to estimate the whole-body retention. The limitations of such an approach are addressed in this study by developing and validating a more advanced computational dosimetry approach using Monte Carlo (MC) simulations in combination with flexible and realistic computational phantoms and time activity distribution curves from reference biokinetic models. Measurements of the ambient dose rate equivalent Ḣ*(10) at 1 m from the NM patient have been successfully compared against MC simulations with 5 different codes using the ICRP adult reference computational voxel phantoms, for typical clinical procedures with 99mTc-HDP/MDP, 18FDG and Na131I. All measurement data fall in the 95
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关键词
Nuclear medicine patients,Caregivers,Release criteria,Monte Carlo,Computational models
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