Synthesis of amide functionlized bidentate NHC-Pd complex for application as catalyst in Suzuki‐Miyaura cross-coupling, in distilled water, under mild reaction conditions

An amide functionlized bidentate NHC-Pd complex was successfully prepared by a facile solvothermal methodology from a bridged bis-benzimidazolium chloride and K2PdCl4. The new bidentate NHC-Pd complex has been effectively applied as catalyst in Suzuki-Miyaura cross-coupling reactions of aryl halides with arylboronic acids in distilled water (yields up to 99.0%). The bridged bis-benzimidazolium ligand from the Pd complex, bearing the amide functional groups on the nitrogen atom, showed to distinctly influence the electronic and steric effects on the catalytic process. The potential of application of the new NHC-Pd catalyst in diverse CC bond forming processes, working under environmentally friendly conditions, is further outlined.