Fluconazole-Loaded Ibuprofen In Situ Gel-Based Oral Spray for Oropharyngeal Candidiasis Treatment

Ei Mon Khaing,Setthapong Senarat,Kritamorn Jitrangsri,Thawatchai Phaechamud

AAPS PharmSciTech（2024）

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摘要

Oral candidiasis is a fungal infection affecting the oral mucous membrane, and this research specifically addresses on a localized treatment through fluconazole-loaded ibuprofen in situ gel-based oral spray. The low solubility of ibuprofen is advantageous for forming a gel when exposed to an aqueous phase. The 1

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fluconazole,ibuprofen,in situ gel,oral spray,oropharyngeal candidiasis

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