IEEE Open Journal of Engineering in Medicine and Biology（2024）
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摘要
Goal:
Parkinson's disease (PD) can lead to gait impairment and Freezing of Gait (FoG). Recent advances in cueing technologies have enhanced mobility in PD patients. While sensor technology and machine learning offer real-time detection for on-demand cueing, existing systems are limited by the usage of smartphones between the sensor(s) and cueing device(s) for data processing. By avoiding this we aim at improving usability, robustness, and detection delay.
Methods:
We present a new technical solution, that runs detection and cueing algorithms directly on the sensing and cueing devices, bypassing the smartphone. This solution relies on edge computing on the devices' hardware. The developed wearable system consists of a single inertial sensor to control a stimulator and enables machine-learning-based FoG detection by classifying detected foot motion phases as either normal or FoG-affected. We demonstrate the system's functionality and safety during on-demand gait-synchronous electrical cueing in two patients, performing freezing of gait assessments. As references, motion phases and FoG episodes have been video-annotated by a clinical expert.
Results:
The analysis confirms adequate gait phase and FoG detection performance. The mobility assistant detected foot motions with a rate above 94 % and classified them with an accuracy of about 84 % into normal or FoG-affected. The FoG detection delay is mainly defined by the foot-motion duration, which is clearly below the delay in existing sliding-window approaches.
Conclusions:
Direct computing on the sensor and cueing devices ensures robust detection of FoG-affected motions for on demand cueing synchronized with the patient's gait. The proposed solution can be easily adopted to other sensor and cueing modalities.
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关键词
Freezing of Gait,On-Demand Cueing,Inertial Sensors,Machine Learning,Edge Computing
