Engineering Microorganisms for Cancer Immunotherapy

ADVANCED HEALTHCARE MATERIALS(2024)

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摘要
Cancer immunotherapy presents a promising approach to fight against cancer by utilizing the immune system. Recently, engineered microorganisms have emerged as a potential strategy in cancer immunotherapy. These microorganisms, including bacteria and viruses, can be designed and modified using synthetic biology and genetic engineering techniques to target cancer cells and modulate the immune system. This review delves into various microorganism-based therapies for cancer immunotherapy, encompassing strategies for enhancing efficacy while ensuring safety and ethical considerations. The development of these therapies holds immense potential in offering innovative personalized treatments for cancer. Engineered microorganisms have emerged as promising tools for cancer immunotherapy. By harnessing the natural capabilities of microorganisms and integrating sophisticated genetic engineering techniques, it is possible to design tailored therapeutic agents capable of targeting and modulating the complex tumor microenvironment. Engineered microorganisms offer a versatile platform for developing innovative and effective cancer treatments that can complement or surpass conventional therapies. image
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关键词
bacterial,cancer immunotherapy,engineering microorganisms,virus
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