Can DRD2 Gene Affect Mathematical Ability? The Impact of a Working Memory-Associated Gene on Mathematical Ability

Abstract Mathematical ability is influenced by various factors, particularly environment and genetics. This study focused on the effect of DRD2, a candidate gene for working memory, on mathematical ability. Our analysis of the DRD2 gene and mathematical ability performance in child participants revealed associations between the DRD2 gene and mathematical ability. It was found that individual's mathematical abilities are influenced by single nucleotide polymorphisms (SNPs) in DRD2, both in the form of haplotypes and in the way the gene interacts with parental education. The results also showed that mathematical ability is influenced by multiple genes. These findings suggest that dopaminergic genes may be linked to mathematical ability. Additionally, dopaminergic genes affect the development of children's mathematical ability by regulating working memory and related brain functions and structures. This study provides important insights into the genetic basis of mathematical ability and offers guidance for individual learning and education.