Research progress on piperidine-containing compounds as agrochemicals

Wei Sun, Anjing Liao, Li Lei, Xu Tang,Ya Wang,Jian Wu

Chinese Chemical Letters(2024)

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摘要
Piperidine is a crucial pharmacophore and a special scaffold in the realm of drug discovery. Its flexibility increases the molecule's capability to bind to the receptor. The piperidine-containing compounds are distinguished by their remarkable activity, and are increasingly becoming a vital category of pesticides. In this review, the research progress of piperidines in the discovery of pesticides was updated according to their active characteristics. The structure-activity relationships (SARs), and mechanisms of action of piperidine-containing compounds were also discussed. This article is meant to enable readers to quickly understand piperidines, while providing ideas for creating piperidines with novel structures and unique mechanisms of action.
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关键词
Piperidine,Agrochemicals,Biological activity,Structure-activity relationships,Mechanism of action
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