Unveiling the synergy of NIRS and enrichment technologies: A comprehensive review of in-sorbent-based detection and quantification strategies

This comprehensive review paper aims to captivate the applicability of in-sorbent detection, where near-infrared spectroscopy (NIRS) converges with enrichment technologies. For this purpose, we collected and summarized information regarding the combination of several sophisticated analytical enrichment techniques with NIRS to further explore and develop this synergistic approach. Peer-reviewed publications, matching the criteria of in situ NIR measurements prior analyte elution, have been collected, investigated, and concluded within this review. Investigations according to used materials, commercial or self-made, composition, organic or inorganic and applied analytical methodologies have been carried out. Applications extending over a multitude of chemical fields, from environmental to medicinal applications. As this review concludes, the combination of these techniques further expands the applicability of NIRS and moreover tries to solve the long-standing issue of the comparably low sensitivity regarding this vibrational technique.