Promising New Diagnostic and Treatment Modalities for Allergic Rhinitis What's Coming Next?

Novel diagnostic tests-including nasal allergen -specific IgE and basophil activation testing-may help differentiate patients with LAR. Surgical approaches including septoplasty, ITR, NSB reduction, and posterior nasal nerve ablation may improve symptoms in patients whose symptoms are refractory to medical therapy, though high -quality evidence is lacking in the AR population. Intralymphatic and epicutaneous immunotherapy have potential to improve adherence to AIT, though head -to -head comparisons with current standard of care treatments are lacking and studies reporting long-term outcomes are needed. Immunomodulatory agents in combination with SCIT may improve tolerance of SCIT but reports to date do not demonstrate a clear benefit in symptom alleviation. Future research should focus on these potential and promising diagnostic and testing options to advance the field of AR (Table 1).