Photoinduced Direct Carbamoylation of Ethers with Isocyanates towards the Synthesis of -Amide-Substituted Ether Derivatives

Photoinduced carbamoylation of ethers using isocyanates asamide sources was accomplished under mild and environmentallyfriendly reaction conditions. A series of isocyanates were tolerated inthis protocol to construct alpha-amide-substituted ether derivatives withdesired yields. The method featured broad substrate scope and goodfunctional group tolerance, which could play an important role in theconstruction of biological molecules with ethers