Mllerian-type carcinosarcoma arising in gastric endometriosis: Case report and review of the literature

Although endometriosis is a common condition, both extrapelvic endometriosis and endometriosis associated malignancy (EAM) are rare. We describe the first reported case of a patient with Mullerian-type carcinosarcoma arising in gastric endometriosis. Imaging findings, including (A) CT demonstrating cystic lesion emanating from the lesser curvature in the proximal stomach and (B) EUS with submucosal cystic mass measuring 10.3 cm, located 3 cm distal to gastroesophageal junction, with internal solid component; and final pathology, including (C) opened 11.0 x 7.6 x 3.8 cm cystic lesion with nodular excrescences in the gastric body near the lesser curvature, (D) areas of squamous differentiation, (E) chondrosarcomatous component, (F) solid areas composed of poorly differentiated cells, suggestive of a dedifferentiated component with readily identifiable mitotic figures, (G) background of endometriosis, and (H) carcinomatous component with patchy PAX-8 nuclear staining.image