Outcomes After Lung Transplantation Performed Using Elective Cardiopulmonary Bypass: A Single Center Experience

Purpose There remains significant variability in the use of intraoperative mechanical circulatory support in lung transplantation. This report details our outcomes using elective CPB in lung transplantation. Methods We performed a single institution analysis of consecutively enrolled patients who underwent isolated lung transplantation between August 2020 and April 2023. Primary outcomes included rates of grade 3 PGD and one-year survival. Results 40 consecutive lung transplants were performed on CBP over the study period. The average PaO2/FiO2 at 72 hours was 369.7+121.4, with grade 3 PGD occurring in two patients (5%). The median intra-operative packed red blood cell transfusion requirement was 300 (93.75-727.5) mL. Freedom from non-elective re-operation was 82.5% (n=33). Mortality was 0% at 90-days, and one-year survival was 90.5%. Conclusion Lung transplantation can be safely performed with elective CPB support.