Synergistic Effects of Inhaled Aztreonam Plus Tobramycin on Hypermutable Cystic Fibrosis Pseudomonas Aeruginosa Isolates in a Dynamic Biofilm Model Evaluated by Mechanism-Based Modelling and Whole Genome Sequencing.
International Journal of Antimicrobial Agents（2024）
Key words
Combination therapy,Dynamic biofilm model,Hypermutator,Mathematical modelling,Pseudomonas aeruginosa,Resistance mechanisms
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