Biosynthesis of copper oxide nanoparticles using Tecoma stans flower extract and its antibacterial, anticancer, and photocatalytic activities

Now a days, green synthesis of metallic nanoparticles obtained huge special attention owing to their safe, biocompatible and biodegradable nature. Here, we describe the green synthesis of copper oxide nanoparticles (CuO NPs) using Tecoma stans (T. stans) flower extract. The physico-chemical properties of the CuO NPs were studied using different characterization techniques. The UV Visible spectrum showed a characteristic peak at 360 nm confirming the synthesis of green CuO NPs. FE-SEM study clearly indicated that synthesized CuO NPs are in spherical shaped morphologies. The green synthesized CuO NPs were carried out bactericidal activity against various clinical pathogens by agar well diffusion techniques. Interestingly, CuO NPs were exhibited very good bacterial killing efficiency against of Bacillus subtilis and Pseudomonas aeruginosa bacteria. The in vitro anticancer activity of the T. stans flower mediated CuO NPs were tested against A549 lung cancer cell line. Further, AO/EtBr staining assay used to determine the apoptotic changes in cancer cell treated with CuO NPs were identified by fluorescence microscopy. The dye-degrading capability of the synthesized CuO NPs were assessed against methylene blue dye (MB) molecules. Finally, this study reveals that the synthesized nanomaterials could performed as a promising candidate in numerous biomedical applications like antimicrobial, anticancer, and dye degradation system.