Anticoagulation in venous thromboembolism for the general physician

Katherine Stark,Abhinav Mathur, Mohammed M. Khan

JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH(2024)

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摘要
Venous thromboembolism (VTE) is frequently encountered across various specialties. The management of VTE has become more nuanced, requiring consideration of several factors when deciding on the choice and duration of anticoagulation. This evidence-based review article summarises the current practice and evidence behind anticoagulation in VTE, incorporating national and international guidelines. Factors influencing decision-making around the choice and duration of anticoagulation, along with special circumstances such as cancer and antiphospholipid syndrome, are discussed. The clinical utility of thrombophilia screening is also addressed.
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关键词
Venous thromboembolism,anticoagulation,provoked,unprovoked,direct oral anticoagulants,warfarin,low molecular weight heparin,renal impairment,hepatic impairment,obesity,cancer,antiphospholipid syndrome,thrombophilia screening,bleeding risk
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