Lung Transplantation for Familial Diffuse Pulmonary Ossification

We report extremely rare three cases of familial idiopathic diffuse pulmonary ossification, two of three received lung transplantation and the other one is listed for lung transplantation. The clinical courses of family members varied greatly, and rapid deterioration could occur; therefore, early and close examination is recommended for transplant registration. During transplantation, the lungs appeared and felt exactly like a “pumice stone” and could not collapse, and good visual field was not easily obtained. Both patients had no recurrence of pulmonary ossification for more than two years.