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Discovery of CBPD-409 and CBPD-268 As Highly Potent and Orally Efficacious CBP/p300 PROTAC Degraders for the Treatment of Castration-Resistant Prostate Cancer

Zhixiang Chen,Mi Wang,Dimin Wu,Lijie Zhao,Tianfeng Xu,Hoda Metwally,Yu Wang,Donna McEachern,Wei Jiang,Longchuan Bai,Jie Luo,Meilin Wang,Ruiting Li,John Takyi-Williams,Lu Wang,Qiuxia Li,Bo Wen,Duxin Sun,Arul M. Chinnaiyan,Shaomeng Wang

Cancer Research（2024）

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