Drug-induced transitions from micelles to vesicles in ionic surfactant solutions

Ilaria Cusano, Inbal Ionita, Pedro Rodriguez Gonzalez,Dganit Danino,Nino Grizzuti,Rossana Pasquino

Colloids and Surfaces A: Physicochemical and Engineering Aspects（2024）

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摘要

Surfactant solutions play key roles in scientific research and technological applications. Here we investigated solutions that combined an ionic surfactant, Cetylpyridinium Chloride (CPyCl), with a non-steroidal, anti-inflammatory drug, Sodium Diclofenac (Diclo). The study covered a wide range of compositions and utilized both rheology and Cryogenic-Electron Microscopy (Cryo-EM). The solutions were prepared at three different concentrations of CPyCl: 5.0mM, 16.7mM and 33.0mM, and we maintained the ratio of surfactant to salt, R=CPyCl/Diclo, within the range of 0.4更多

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关键词

surfactants,rheology,vesicles,microscopy,branching,wormlike micelles,morphology

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